Radikalita chirurgické léčby a postavení
adjuvantní chemoterapie u nádorů ovaria
hraniční malignity
Ševčík L.1, Klát J.1, Koliba P.1, Čuřík R.2
1Porodnicko-gynekologická klinika FNsP, Ostrava, přednosta MUDr. P. Koliba, CSc. 2Ústav patologie FNsP, Ostrava, přednosta MUDr. R. Čuřík |
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Souhrn:
Objective: Evaluation of the benefi t of the radical surgical therapy in the assessment of prognostic
factors and indication of adjuvant therapy in patients with borderline tumors of ovary.
Design: Retrospective study.
Setting: Department of Obstetrics and Gynecology, University Hospital, Ostrava.
Methods: The group consists of 26 patients operated on our department, 12 of which underwent
restaging operation after insuffi cient primary surgery in different hospital and14 underwent
primary surgery in our department. The average age was 42.9 years.
Results: Radical surgery with regional lymphadenectomy was performed in 18 cases (69%) and
non-radical in 8 cases (31%). In 7 patients (27%) fertility preservation operation was done. According
to histological results 19 tumors (73%) were of serous type, 7 being of mucinous type
(27%). There were no other histological types in our group. The lymphnodes were positive in 4
cases (22%) out of 18. Eight patients were indicated for adjuvant chemotherapy (31%), 4 of them
for regional lymphnodes positivity, 2 for peritoneal implants, 1 patient for tumor residuum. The
last case was a patient with tumor duplicity of a borderline tumor of ovary stage FIGO IIC and
corporal carcinoma stage FIGO IB.
We had one case of recurrence after fertility preservation surgery. There was no case of pregnancy
yet.
Conclusions: Borderline tumors of ovary have good prognosis and low recurrence rate. In spite
of that, there exists a group of women with higher risk of recurrence and disease progression
which can be fatal. These patients may benefi t from adjuvant therapy, which is indicated after
evaluation of risk factors ideally acquired from the radical surgery.
Klíčová slova:
borderline tumor of ovary, radical surgery, lymphadenectomy, chemotherapy
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