Systémová imunita u pacientek s rekurentní
vulvovaginální kandidózou
Jílek P.1, Špaček J.2, Buchta V.1,4, Kučera Z.1, Drahošová M.3, Förstl M.4, Andrýs C.3
1Katedra biologických a lékařských věd, Farmaceutická fakulta UK v Hradci Králové, vedoucí doc. RNDr. V. Semecký, CSc. 2Porodnická a gynekologická klinika, FN a LF UK v Hradci Králové, přednosta doc. MUDr. J. Tošner, CSc. 3Ústav klinické imunologie a alergologie, FN a LF UK v Hradci Králové, přednosta MUDr. O. Kopecký, CSc. 4Ústav klinické mikrobiologie, FN a LF UK v Hradci Králové, přednosta prof. MUDr. M. Špliňo, DrSc. |
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Souhrn:
Objective: This study was undertaken to characterize systemic immunity in the patients with recurrent
vulvovaginal candidiasis.
Subject: original prospective study.
Setting: 1. Department of Biological and Medical sciences, Charles University in Prague, Faculty of
Pharmacy, Hradec Kralove, 2. Department of Obstetrics and Gynaecology, Medical Faculty, Hradec
Kralove, Charles University in Prague, 3. Department of Clinical Immunology and Allergology,
University Hospital, Hradec Kralove, 4. Department of Clinical Microbiology, University Hospital,
Hradec Kralove, Czech republic.
Subject and method: Basic immunological parameters in 44 patients with recurrent vulvovaginal candidiasis
were investigated and analyzed in this longitudinal follow-up study.
Conclusion: Although there is no fundamental disturbance in systemic immunity in patients with recurrent
vulvovaginal candidiasis and the majority of systemic immunological parameters in the patients
were within normal range, some subtle changes of a few parameters of humoral and cellular immunity
in contrast to the controls were identified.
Klíčová slova:
recurrent vulvovaginal candidiasis, humoral immunity, cell immunity
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