The aim of this article is to present the relation between Helicobacter pylori infection and immunological disorders based on current literature data. The relation has been analysed in patients with MALT lymphoma, autoimmune diseases and immunodeficiency or on immunosuppressive therapy. H. pylori acting chronically in the gastric mucosa causes immunological stimulus which may exert systemic effects and influence on some extra-digestive disorders. The course of the gastric H. pylori infection and extra-digestive manifestations are associated with both bacterial and host factors determining the immune response against H. pylori.

        Klíčová slova: Helicobacter pylori infection – immunological disorders