Applications of molecularly imprinted
polymers in analytical and
pharmaceutical chemistry
LACHOVÁ M.1, LEHOTAY J.1, ČIŽMÁRIK J.2
1Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovak Republic 2Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Bratislava, Slovak Republic |
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Fulltext
Summary:
Application of molecularly imprinted polymers in analytical and pharmaceutical chemistry
The paper reviews recent developments in the use of molecularly imprinted polymers in several analytical
techniques, such as solid-phase extraction, liquid chromatography, capillary electrophoresis,
capillary electrochromatography, and as selective sorbents in chemical sensors. Molecular imprinting
is achieved by the interaction between complementary groups in a template molecule and functional
monomer units. The benefits of imprinted polymers are low cost, storage stability, high
mechanical strength, repeated operations without loss of activity, and potential application to a wide
range of target molecules.
Key words:
molecularly imprinted polymers – solid-phase extraction – liquid chromatography –
electrochromatography – membranes – sensors
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