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  Česky / Czech version Čes. slov. Farm., 2004; 53, 300–303
 
Carbomers and Their Use in Pharmaceutical Technology 
RABIŠKOVÁ M.1, SEDLÁKOVÁ M.1, VITKOVÁ M.2, KUNA M.1 

1Ústav technologie léků Farmaceutické fakulty Veterinární a farmaceutické univerzity, Brno 2Katedra galenickej farmácie Farmaceutickej fakulty Univerzity Komenského, Bratislava
 


Summary:

       Carbomers, high-molecular polymers based on acrylic acid, are employed in the technology of drugs as auxiliary substances acting as emulsifiers, gel-forming substances, stabilizers of suspensions, and binders in tablets. Their properties are utilized to control release as well as to improve biological availability of drugs. They are physiologically inert, non-sensitizing, and possess excellent thermal stability. They are used for various routes of administration: topical, oral and peroral, vaginal and rectal.

        Key words: carbomers – auxiliary substances – dosage forms – properties – use
       

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