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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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Česky / Czech version | Čes. slov. Farm., 2004; 53, 300–303 |
Carbomers and Their Use in Pharmaceutical Technology RABIŠKOVÁ M.1, SEDLÁKOVÁ M.1, VITKOVÁ M.2, KUNA M.1 1Ústav technologie léků Farmaceutické fakulty Veterinární a farmaceutické univerzity, Brno 2Katedra galenickej farmácie Farmaceutickej fakulty Univerzity Komenského, Bratislava |
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Summary: Carbomers, high-molecular polymers based on acrylic acid, are employed in the technology of drugs
as auxiliary substances acting as emulsifiers, gel-forming substances, stabilizers of suspensions, and
binders in tablets. Their properties are utilized to control release as well as to improve biological
availability of drugs. They are physiologically inert, non-sensitizing, and possess excellent thermal
stability. They are used for various routes of administration: topical, oral and peroral, vaginal and
rectal.
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