CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ | |
Journals - Article | |
Česky / Czech version | Čes. slov. Farm., 2004; 53, 248–251 |
Isolation and Characterization of Active Compounds from Aloe vera with Possible Role
in Skin Protection KOŠŤÁLOVÁ D., BEZÁKOVÁ L.1, OBLOŽINSKÝ M.1, KARDOŠOVÁ A.2 Katedra farmakognózie a botaniky Farmaceutickej fakulty Univerzity Komenského, Bratislava 1Katedra bunkovej a molekulárnej biológie liečiv Farmaceutickej fakulty Univerzity Komenského, Bratislava 2Chemický ústav SAV, Bratislava |
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Summary: Aloe vera is widely used in food supplements, beverages, pharmaceuticals, and cosmetics. It has been
long recognized as an effective natural remedy for its wound-healing properties and its positive
influence on other inflammatory skin disorders. Major proteins and mono- and polysaccharides were
identified and analysed from Aloe vera commercial extract. Molecular weight of proteins calculated
from the sets ofmolecular weight reference standards, ranged from 70 kDa for the largest to 14 kDa
for the smallest ones. IR spectral analysis of the carbohydrate fraction shows that the main
carbohydrate copound is acetylated (1→4)-β-D-mannan substituated with D-galactose and D-glucose.
The results have shown that proteins and polysaccharides are a necessary component in the
study of biological activity of Aloe vera leaf extract.
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