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  Česky / Czech version Čes. a Slov. Farm., 51, 2002, No. 1, p. 11-16
 
Pharmaceutical Importance ofAllium sativum L. 2. Antibacterial Effect 
SOVOVÁ M., SOVA P. 

Katedra farmaceutické botaniky a ekologie Farmaceutické fakulty Univerzity Karlovy, Hradec Králové Výzkumný ústav - odbor léčiv, Pliva-Lachema a.s., Brno
 


Summary:

       The communication summarizes mainly netyly obtained experimental findings confirming the antibacterial effect of garlic preparations (powders, extracts, juice, essential oil, oil macerate) and their individual components. It also reports the effectiveness of substances netyly isolated from the oil macerate (iso-E-l0-devinylajoene, Z-10-devinylajoene, and three, or five thiosulfinates). The effect on the tested bacteria included bere is, according to new evidence, indisputable. The paper has purposefully excluded the action of garlic against the widely distributed bacteria Helicobacter pylori, which causes chronic gastritis, gastric and duodenal ulcers 57, 5s). The findings concerning this matter will be published in the following communication.

        Key words: Album sativum - antibacterial effect - extracts - garlic powders - isolates
       

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