This paper is the 21st communication in the series of review papers on the development of antituberculotics and the 10th communication summarizing the papers on the development of antituberculotics in recent 15 years. The first seven communications were devoted to heterocyclic compounds, the eighth one to the compounds containing an alkylsulfanyl group in the pharmacophore. The present paper sums up information concerning the compounds not containing a heterocycle in the pharmacophore which are not derivatives of carboxylic acids either. This completes the series of communications recording the development of antituberculotics in the recent period. The communication records papers published since 1980 because it intends to link up with a review paper puslished in 1982 (Českoslov. Farm., 1982; 31, 353–360).

        Key words: tuberculostatics – mycobacteria – Mycobacterium tuberculosis