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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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| Česky / Czech version | Čes. slov. Farm. 52, 2003, No. 6, p. 291–294 |
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A Novel Group of Potential Antituberculotic Agents: Antimycobacterial N-Benzylsalicylamides WAISSER K., PEŘINA M., BOUDOVÁ I., KUNEŠ J., KAUSTOVÁ J.1 Katedra anorganické a organické chemie Farmaceutické fakulty Univerzity Karlovy, Hradec Králové1 Oddělení pro diagnostiku mykobakterií – Krajská hygienická stanice, Ostrava |
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Summary: Linking up with a previous study of antimycobacterial compounds, several groups of N-benzylsalicylamides
were prepared and their antimycobacterial activities against the strains Mycobacterium
tuberculosis,Mycobacterium kansasii, and Mycobacterium aviumwere evaluated.The obtained data
were analyzed by Free-Wilson method in comparison with their isosteric analogues of 3-hydroxypicolinic
and 2-sulfanylbenzoic acids described in the previous communication.
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