CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ | |
Journals - Article | |
Česky / Czech version | Čes. a Slov. Farm., 51, 2002, No. 3, p. 154-156 |
Study of Local Anesthetics
CLX. Determination of the Critical Micellar Concentration (c.m.c.) in Series of the Derivates Piperidinoethylesters of 3-Alkoxyphenylcarbamic Acid
ANDRIAMAINTY F., ČIŽMÁRIK J., MARIŠČÁKOVÁ Z Katedra farmaceutickej chémie Farmaceutickej fakulty Univerzity Komenského, Bratislava |
|
Summary: We have determined the critical micellar concentration (c.m.c) of the derivates type piperidinoethyl esters 3-alkoxy phenylcarbamic in the medium 0.05 moUl and 0.2/moUl NaCI for using spectrophotometry methods in the UV region of the spectrum at temperature T=25 °C and pH=4.5-5.0. We found the parabolic dependence of the -ln(c.m.c.) on the (n) number of the carbon in the alkoxy substituent chain. Further, we have observed the facility formation of the micelle at the solution of 0.2 moUl than 0.05 moUl NaCI.
|
|
Order this issue
|
BACK TO CONTENTS | ||
| HOME PAGE | CODE PAGE | CZECH VERSION | |
© 1998 - 2008 CZECH MEDICAL ASSOCIATION J. E. PURKYNĚ |
Created by: NT Servis, s.r.o., hosted by P.E.S. consulting, s.r.o. |
WEBMASTER |