The Alkylsulfanyl Group - the Pharmacophore of Antimycobacterial Activity Tuberculosis ranks among the most widely spread infectious diseases and the need to find new antituberculotics has become more and more urgent. The present review paper aims at the compounds containing an alkylsulfanyl group which can be considered the pharmacophore of antituberculotic activity. The alkylsulfanyl group is bound to various heterocycles, condensed systems, and there is also a bond to the aliphatic strukture. The activities of some compounds discussed in the resent paper are comparable with those of the antituberculotics in current use and therefore they could be introduced finto practice, or at least suggest further direction of development. The present survey is based on the journal Chemical Abstracts.

        Key words: tuberculostatics - antituberculotics - mycobacteria - alkylsulfanyl group