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  Česky / Czech version Čes. a slov. Farm. 49, 2000, No. 6, p. 288–298
 
Kojic Acid and Its Derivatives as Potential Drugs 
UHER M., CHALABALA M. 1 , ČIŽMÁRIK J. 2 

Katedra organickej chémie Chemickotechnologickej fakulty Slovenskej technickej univerzity,
 


Summary:

       The review paper studies kojic acid, a secondary metabolite of fibrous fungi, as a carrier chemical structure of potential pharmaceuticals. The examined preparative procedures, physico-chemical and biologic properties, and especially the antifungal and antileukemic effects of the parent kojic acid indicate that novel potential drugs can be developed on its basis.

        Key words: kojic acid – 4-H-pyran-4-ones – kojic acid derivatives – antifungal and antileucemic activity
       

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