Soft gelatin capsules are a dosage form suitable particularly for administration of sensitive drugs posing technological problems. They mask an unpleasant taste or smell of the drug and the colour combinations increase the safety of therapy by excluding interchangings. Their manufacture is undemanding, it depends on the quality of gelatin and the gelatin mass for the shell of the capsules, on the properties of the fill, on mutual interactions between the fill and the shell, and on a special know-how, which is an unconditional precondition of successful manufacture of this dosage form The paper is a review characterizing soft gelatin capsules, processes of their manufactures, and quality evaluation.

        Key words: soft gelatine capsules – capsule fill – capsule shell – processes of manufacture – evaluation – biological availability of drug