Summary:
The effect of the incorporation of different concentrations of magnesium stearate (0, 0.4, 0.8, and
1.2 %) on the texture of the tablets from Avicel PH 101 was investigated by means of the examination
of their tensile strength and the values of Weibull’s modules. It has been found that with an
increasing forming pressure the decrease in the tensile strength of tablets is increased. No
significant difference in the decrease in tensile strength was found between stearate concentrations
of 0.4 and 0.8 %. The incorporation of magnesium stearate into the tableting material, by decreasing
the friction between the particles, minimizes possible incidence of more marked disorders in the
texture of tablets.
Key words:
Avicel PH 101 – magnesium stearate – tensile strength of tablets – structure
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