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  Česky / Czech version Čes. a slov. Farm. 48, 1999, No. 6, p. 247–251
 
The Use of the Concept of the Pharmacophore in Drug Design 
SMIEŠKO M., REMKO M. 

 


Summary:

       The application of the pharmacophore concept to design new drugs is discussed. The focus is on the application of computer–assisted drug design methods (CADD) in the discovery of new leads.

        Key words: drug design – pharmacophore – database – molecular modelling – conformational analysis
       

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