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  Česky / Czech version Pracov. Lék., 58, 2006, No. 1, p. 33–37
 
Chronic Obstructive Pulmonary Disease in Workers Exposed to SiO2 
Hajduková Z. 

Klinika chorob z povolání FNsP Ostrava-Poruba, přednostka MUDr. Zdeňka Hajduková, Ph.D.
 


Summary:

       The objective of the paper is to summarize current data on influence of quartz on the development of chronic bronchitis and chronic obstructive pulmonary disease (COPD). The aim of the paper is to justify integration of COPD caused by SiO2 to the list of occupational diseases to be reviewed. The author submits a review of epidemiological surveys, which confirm the role of SiO2 in the progress of chronic bronchitis and COPD.

        Key words: stages of COPD, pathophysiology of SiO2 activity, chronic bronchitis, oxidative stress, inflammatory markers BAL, smoking
       

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