Antilipoxygenase Activity and the Trace Elements Content of Aloe vera in Relation to the Therapeutical
Effect
BEZÁKOVÁ L, OBLOŽINSKÝ M., SÝKOROVÁ M.1, PAULÍKOVÁ I., KOŠŤÁLOVÁ D.2
Katedra bunkovej a molekulárnej biologie liečiv Farmaceutickej fakulty Univerzity Komenského, Bratislava 1 Katedra farmaceutickej analýzy a nukleárnej farmacie Farmaceutickej fakulty Univerzity 2 Katedra farmakognózie a botaniky Farmaceutickej fakulty Univerzity Komenského, Bratislava |
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Summary:
Aloe vera is a rich source of many natural-health-promoting substances. The results of contemporary research on animal models indicate that the extracts háve an antiinflammatory property. In this work the results of some in vitro experiments are shown: determination of the inhibitory effect of the Aloe vera extracts on the activity of partially purified lipoxygenase from the rat lung cytosol fraction, and quantitative determination of the trace ele-ments presented in the extract (Mn, Fe, Cu, Zn) carried out by using the x-ray fluorescence analysis. The fin-dings could explain the inhibitory effect (antilipoxygenase activity) of the Aloe vera extract in the acute inflam-mation process, expecially in the topical application for healing of minor burns and skin ulcers
Key words:
Aloe vera - lipoxygenase - trace elements - x-ray fluorescence analysis
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