The authors discuss balic diagnostic and therapeutic procedures in head-brain injury treatment procedures. Those are divided finto two phases: before and after CT scan and implemenxation of ICP monitoring. During the hrst phase, diagnostic and therapeutic procedures are based on clinical assessmenx; during the latter phase, procedures are based on ICP and CPP monitoring. Based on regression analysis of both parameers, the authors postulaxe a conclusion Chat stresses the importance of ICP/CPP index which is supposed to be not ohly a criterion of inxracranial dysfunction but also a parametrr upon which a rational therapeutic approach can be defireed. There is importanx to add jugular bulb oximetry and monitoring of PtiOz to ICP/CPP monitoring.

        Key words: intracranial hypertension - ICP - CPP - ICP/CPP - regression analysis - therapeutic concept