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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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| Česky / Czech version | Čes. - slov. Derm. 77, 2002, No. 4, 172-174 |
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Granulomatosis Orofacialis in Two Monozygotic Twins Kolibášová K.1, Hegyi E.1, Lukáčová Z.1, Buc M.2, Lukáčová M.3, Doležalová A.4, Hrubiško M.5, Ondriáš F.6 1Kožná klinika Slovenskej Postgraduálnej Akadémie Medicíny (SPAM), NsP Ružinov, Bratislava prednostka doc. MUDr. Klaudia Kolibášová, PhD. 2Imunologický ústav Lekárskej fakulty Univerzity Komenského, Bratislava prednosta prof. MUDr. Milan Buc, DrSc. 3Centrum lekárskej genetiky, Fakultná nemocnica Bratislava primárka MUDr. M. Lukáčová, CSc. 4I. dermatovenerologická klinika, LF UK, Bratislava prednosta prof. MUDr. Jozef Buchvald, DrSc. 5Národný ústav tuberkulózy a respiračných chorôb, Bratislava, alergologicko-imunologická ambulancia primár MUDr. Martin Hrubiško, CSc. 6Patologické oddelenie NsP Ružinov, Bratislava primár doc. MUDr. F. Ondriáš, CSc. |
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Summary: The authors detected monozygotic twins who developed at the age of 30 years permanent not
painful oedema of the lower lip. In the case-history oedema of the lip was recorded in the probands’
grandmother. Epicutaneous tests (the patients grow vegetables and flowers) were negative. As to
routine tests the early response to Peru balsam was positive, in one sibling also the late response to
propolis. Histological examination confirmed the diagnosis of granulomatous cheilitis. Wedge-shaped
excision from the lower lip and administration of metronidazol were not successful.
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