Summary:
Hair loss is a frequent phenomenon which may cause psychological problems in some patients.
Androgenetic alopecia occupies a special position and belongs to the group of telogen hair loss. There
have been demonstrated hormonal abnormalities in androgenetic alopecia. Clinically it is similar to
other types of diffuse alopecias (alopecia in hypo- or hyperthyreoidism, alopecia following parturition,
postfebrile alopecia, etc.). In females suffering from diffuse alopecia and with signs of virilization
it is necessary to investigate a potential hyperandrogenic syndrome (diseases of adrenals or
ovaria). In females it is recommended to test for DHEA (dehydroepiandrosterone) sulfate which is
exclusively of adrenal origin, and for testosterone (adrenals, ovaria). In both genders it is recommended
to examine thyroxin and TSH (thyroid stimulating hormone) levels, blood count, zinc, and
ferritin. Iron deficiency is a frequent and reversible cause of a telogenic effluvium. Itmayaccompany
androgenetic alopecia. The blood ferritin level reveals the iron capacity in cells, including follicular
cells, more precisely than the plasma iron value.
In the treatment of androgenetic alopecia in males, finasterid and minoxidil are recommended
(by the FDA), in females antiandrogens (cytoproteron acetate), estrogens (ethinylestradiol) and
minoxidil. Locally applied retinoids (tretinoin) increase the effects of minoxidil. The trichometric
programwith the aid of MicroDermHair analysis determines the ratio of anagenic and telogenic hair.
Within the framework of the program there are in play data-base and archiving functions (50). The
method replaces the classical trichogram.
Key words:
androgenetic alopecia - hyperandrogenic syndrome - examination - treatment
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