The granular cell tumour (GCT) is a benign neuronal tumour. It is supposed, that the tumour originate from altered Schwann cells. Cutaneous and subcutaneous GCT are the most common, but they have been found in internal organs as well. Malignant GCT constitute fewer than 2% of all granular cell tumours. The GCT of the esophagus is relatively rare tumour, nonepithelial in origin, localized in the mucosa and submucosa, most frequently with a benign clinical course. The authors describe a case report of a GCT of the esophagus, which was after the endosonographic examination treated by endoscopic resection. Histologically there were two notable features: pleomorphism of the nuclei and the spindle appearence of some cells („spindling“). According some authors these features may label a tumour as being of uncertain malignant potential. Long time follow up of the patient is necessary.

        Key words: granular cell tumour of the esophagus, endoscopic resection