CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ | |
Journals - Article | |
Česky / Czech version | Čes. - slov. Derm. 77, 2002, No. 5 213-216 |
Skin Aspergillosis in a Patient after Allogenic Transplantation of Haematopoietic
Stem Cells Cetkovská P.1, Pizinger K.1, Karas M.2 1Dermatovenerologická klinika, LF UK Plzeň přednosta prof. MUDr. Vladimír Resl, CSc. 2Hematologicko-onkologické oddělení, FN Plzeň vedoucí prim. MUDr. Vladimír Koza |
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Summary: Skin infections are a frequent complication associated with transplantation of haematopoietic
stem cells, as due to reduced immunity the patients develop otherwise quite rare opportune
infections. The manifestations may be localized only in the skin or affect also other organs. As an
example of disseminated infection the authors present the case of a 48-year-old man treated by
allogenic transplantation of peripheral stem cells who developed seven months after transplantation
disseminated skin aspergillosis. Concurrently signs of cytomegaloviral and bacterial infection were
detected and despite intense anti-infectious therapy the patient died. In immunosuppressed patients
it is important to keep in mind the increasing incidence of various skin infections which may take
an atypical course and have a very adverse prognosis.
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