Summary:
Consistent with the worldwide development of nuclear medicine, in the Czech Republic in 1987 to 1996 partly
the spectrum of used radiopharmaceutical preparations and their ratio changed. In the majority of radiopharmaceutical
preparations the mean administered activity increased by 20 to 80 % and the range of activities administered in
different departments diminished somewhat. Adherence to principles of radiation protection of patients is assisted
by guidelines of administered activities of radiopharmaceutical preparations laid down in new regulations on radiation
protection valid in the CR from the middle of 1997. The radiation burden associated with the majority of examinations
in nuclear medicine expressed as the effective dose is comparable with the radiation burden of radiodiagnostic
examinations, only after administration of preparations with
131
I,
201
Tl,
67
Ga and
111
In it is markedly higher. Based
on knowledge of the effective dose it may be concluded that the lifetime extra risk of a fatal tumour due to
administration of radiopharmaceutical preparations is by two to three orders lower than the lifetime risk of
spontaneous development of fatal tumours. A special feature of radiation risk is its hypothetical character - it is
frequently projected into the distant future of human life, contrary to immediate non-radiation risks of some medical
procedures and risks in the living environment which frequently are higher. Any examination using ionising radiation
can be made only if the expected health benefit for the patient is significantly greater than the radiation risk. Excessive
fear of radiation risk should not lead to refusal of justified examinations with possible subsequent serious health
damage for the patient.
Key words:
radiopharmaceutical preparations, mean administered activity, radiation load, effective dose, radiation
risk, nuclear medicine, radiation protection.
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