We evaluated haemodynamic stability during the induction of general anaesthesia in the group od 49 patients. For the orotracheal intubation we used nondepolarizing muscle relaxant cisatrcurium which is told not to make a release of histamin. For the induction of general anaesthesia we used etomidate (intravenous induction agent) with sufentanil (opioid). We compared two groups ofpatients who were divided by the severity of cardiovascular conditions, especially coronary heart disease. The application of cisatracurium did not impair followed haemodynamic parameters significantly. Other signs of release of histamin were not noted. Cisatracurium is the Bafe muscle relaxant for the induction of general anaesthesia with haemodynamic stability.

        Key words: cisatracurium - etomidate - sufentanil - haemodynamic stability