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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
| Journals - Article | |
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| Česky / Czech version | Pracov. Lék., 54, 2002, No. 4, p. 186 - 189 |
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Toxic Impairment of the Liver with Trinitrotoluene Hassmanová V.1, Hůlek P.2, Nožička J.3 1Klinika nemocí z povolání UK Praha, Lékařská fakulta a Fakultní nemocnice Hradec Králové, zastupující přednosta MUDr. Eva Korolová 2I. interní klinika UK Praha, Lékařská fakulta a Fakultní nemocnice Hradec Králové, přednosta doc. MUDr. Miloslav Pleskot, CSc. 3Fingerlandův ústav patologie UK Praha, Lékařská fakulta a Fakultní nemocnice Hradec Králové, přednosta, prof. MUDr. Ivo Šteiner, CSc. |
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Summary: The paper reports non-alcoholic steatohepatitis (NASH) in a 55-year-old man who worked for 22 years under a significant
trinitrotoluene risk. The found disease is an example of the fact that non too significant pathological laboratory findings can be
accompanied by a serious histological picture showing not only liver steatosis, with contributing concurrent hyperlipoproteinaemia,
but primarily showing marked necrotic-inflammatory changes. A sporadic finding of Mallory’s hyaline does not exclude the
participation of alcohol, but certainly there are no sings of alcoholic affection.
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