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  Česky / Czech version Čs. Oftal., 55, 1999, No. 5, p. 296-298
 
Electrophysiology in Hypovitaminosis A 
Svěrák J., Jebavá R., Hejcmanová D., Peregrin J., Sobotka L. * 

 


Summary:

       Electroretinographic examinations performed according to the international standard were used in two patients with alimentary hypovitaminosis A. In one instance a mentally caused long-term deficiency of dietary vitamin A intake was involved ,in the second instance a fistula from the proximal jejunum into the transverse colon. In both instances night blindness was reported. The initial vitamin A values were 1.0 and 0.6 micromol/l resp. and after substitution therapy they rose to 2 micromol/l. While the rod and maximal ERG responses improved gradually, the oscillation potentials remained pathological as regards amplitudes and latencies. We consi- der them therefore a sensitive indicator of the electric sensitivity of the retina also in other cases of confirmed or suspected vitamin A deficiency. The existence and orientation of our metabolic and gerontological clinic provides adequate oportunities for these investigations.

        Key words: hypovitaminosis A, electroretinography, oscillation potentials
       

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