The Importance of Oesophageal Motility Disorders in the Etiopathogenesis of Gastrooesophageal
Reflux in Children
Villarreal R. J.1, Zibolen M.,1, DragulaM.3, BaškaT.3, DibdiakD.2,Murgaš D.2
Klinika detí a dorastu JLF UK a MFN, Martin,1 prednosta prof. MUDr. P. Bánovčin, CSc. Klinika detskej chirurgie JLF UK a MFN, Martin,2 prednosta MUDr. M. Dragula, PhD. Ústav epidemiológie JLF UK, Martin,3 vedúci prof. MUDr. Š. Straka, CSc. |
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Summary:
Measurement of the oesophageal pressure is a method that facilitates understanding of the etiopathogenesis of
the gastroesophageal reflux (GER) in children. The authors analysed measurements of the oesophageal pressure
in 40 children, divided into two groups according to the results of 24 hours pH metry. Ineffective motility of the
oesophagus has been found more frequently in children with GER compared to those with normal pH metry (in
proximal oesophagus p < 0.01; in distal oesophagus p < 0.001). The authors also found, that 96% of children with
GER had more than 30% uncoordinated contractions, which is significantly different from children without GER
(p < 0.01). Body weight and proportion of peristaltic contractions were significantly associated both in the proximal
(p < 0.001) and distal (p < 0.001) oesophagus in children without GER, while in children with GER no association
was found. The authors conclude that non-specific disorders of oesophageal motility significantly contribute to
etiopathogenesis of GER in children.
Key words:
gastroesophageal reflux in children, oesophageal motility disorders, oesophageal manometry
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