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  Česky / Czech version Vnitř. Lék., 47, 2001, No. 11, p. 863-867
 
Absence of the Nocturnal Dip in Blood Pressure as a New Independent Prognostic Factor in Hypertension 
Veselý J 

Ústav patologické fyziologie LF UP, Olomouc, přednosta doc. MUDr. J. Veselý, CSc.
 


Summary:

       Considerable evidence has accumulated indicating that the lack of the normal nocturnal fall in blood pressure (non-dipper) may represent an important prognostic factor in hypertension. This review focuses on clinical studies showing close association between a non-dipper pattern of blood pressure and cardiovascular events such as glomerular capillary hypertension, cerebrovascular events, left ventricular hypertrophy and ventricular arrhythmias. A close relationship between impairment of the circadian rhythm of blood pressure and that of natriuresis is described. The therapeutic profit from the knowledge that a given patient is a non-dipper and/or salt-sensitive is illustrated.

        Key words: Cardiovascular risk factors - Hypertension - Circadian rhythm of blood pressure - Non-dippers - Salt-sensitivity - Microalbuminuria - Diuretics
       

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