Cutaneous amyloidoses represent a group of diseases classified according to the origin of amyloid. Amyloidoses from keratin include lichen amyloidosus, macular amyloidosis, amyloidosis due to actinic damage of keratinocytes and amyloidosis connected to epidermal tumors. AL amyloidoses originate from monoclonal plasmocyte proliferation with increased level of sérum immunoglobulins. Amyloid L originates from their light chains and deposits in various tissues, mainly around vessels. Amyloidoses with A amyloid are connected to chronic inflammatory processes leading to increased level of sérum amyloid A-related pro¬tein that belongs to acute phase proteins. This protein is metabolised into amyloid A in the sérum and depo¬sits around vessels in various tissues in the čase of high sérum levels. Histopathological examination is clue to finál diagnosis in each type of amyloidosis.

        Key words: cutaneous amyloidoses - clinical picture - histopathological pattern - therapy