Egpression of Constitutive and Activation Surface Antigens on Peripheral Blood Platelets of Healthy Adult Subjects (Pilot Study)
Loudová M.1, Vokurková D.1, Hošková J 2, Krejsek J.1
lÚstav klinické imunologie a alergologie Lékařské fakulty UK a FN, Hradec Králové, přednosta MUDr. O. Kopecký, CSc. 20ddělení klinické hematologie FN, Hradec Králové, přednosta prof. MUDr. J. Malý, CSc. |
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Summary:
The authors present normal values of selected Constitutive and activating platelet surface antigens egpression. The results esere obtained by flow cytometry analysis after immunofluorescent staining of the peripheral whole blond specimens from 25 healthy adults. Data are presented as a mean value and standard deviation (SD) of percentage of positive labelled platelets: constitutively egpressed molecules CD9: 94.9 7% (± 2.95), CD31: 92.78 % (± 2.97), CD36: 90.98 % (± 5.25), CD41: 95.62 % (± 2.23), CD42a: 94.98 % (± 2.62), CD42b: 94.13 % (± 2.58), activatinn molecules CD62P: 0.45 % (± 0.33), CD63: 0.32 % (± 0.22). This study is the hrst report in Czech literature.
Key words:
Blond platelets - Constitutive and activating surface antigens - Flow cytometry
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