CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ | |
Journals - Article | |
Česky / Czech version | Čes.-slov. Pediat., 55, 2000, No. 7, p. 448-451. |
Antibodies against PRP Antigen of Haemophilus influenzae Type b (anti PRP Hib) in Paired
Sera of Mothers and Neonates Gajdoš J., Nováková E. 1 , Tancárová K. Detské oddelenie NsP, Levoča, |
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Summary: During a four-year surveillance of haemophilus infections in the Slovak Republic 7% of all cases of invasive
cases in children occurred in children under the age of 3 months. 650 paired mother-neonate samples were
examined with the objective to assess the anti PRP Hib antibody level.
The mean level of PRP antibodies was 3.16 mg/l in mothers and 2.87 mg/l in neonates. The ratio of transmission
of antibodies in individual paired sera was 17 - 98% (mean 91.7 %). 15 % of the neonate s had a level of anti PRP
Hib antibodies lower than 0.5 mg/l.
The authors found that 15 % neonates do not have at the age of 3 months a protective level of anti PRB Hib
antibodies either due to low levels in the mother or due to inadequate transmission of antibodies from the mother.
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