We try to determine if propofol infusion for prolonged anaesthesia (many hours) is safe even for children from 1 to 3 years of age. Thirty children of the studied age were enrolled in the study. We found out that the administration of propofol is devoid of any complications, provided adherence to defined doses and dose regimen. Cardiovascular system of children is not affected. The quality of recovery and recovery time as well as early postoperative period are not affected. We can conclude that propofol, in the hands of an experienced anaesthesiologist, represents a safe anaesthetic agent even for our smallest patients.

        Key words: paediatric anaesthesia – continuous propofol – circulatory stability – quality and speed of recovery from general anaesthesia – endothel