The article presents review of the pathophysiology of brain death and its impact on haemodynamics in the brain death patients.In detail it describes the results of an autonomic storm,influence on the aerobic metabolism,endocrine changes and the histological organ damage.From heart transplantation point of view the authors deal with the myocardial dysfunction.They explain in detail the possibilities for haemodynamic monitoring and optimization in the care of the brain death patients.

        Key words: brain death –organ donor –pathophysiology of brain death –haemodynamic monitoring –haemodynamic optimization