Concentrations of IgG, IgA, IgM, C3 and C4 Complement Constituents in Healthy Children and Children with Dispensary Care of the Allergological Immunological Out-patient Department
Průcha M., Dostál M., Miláček V., Fejt V,, Petrů V., Šrám R.
Oddělení klinické biochemie, hematologie a imunologie, Nemocnice Na Homolce, Praha,l přednosta prof. MUDr. J. Hyánek, DrSc.Ústav experimentální medicíny AV ČR a Krajská hygienická stanice Středočeského kraje, Praha, Laboratoř genetické ekotoxikologie, vedoucí MUDr. R. Šrám, DrSc. Dětské oddělení, NsP, Havlíčkův Brod, přednosta MUDr. V. Miláček. Oddělení dětské alergologie a imunologie, Nemocnice Na Homolce, Praha, přednosta doc. MUDr. V. Petrů, CSc. Oddělení mikrobiologie, NsP, Havlíčkův Brod, přednosta MUDr. P. Linhart. |
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Summary:
During the last 15 years methods for examination of plasma proteins in immunological laboratories changed fundamentally. Examination by radial immunodiffuzion was abondoned in favour of turbidometric methods or lase nephelometry. In the submitted paper the authors compare the concentrations of IgG, IgA, IgM, C3 and C4 Complement constituent in healthy Children without clinical signs of allergic disease or immunodeficiency and in Children under dispensary care of the allergological and immunological out-patient department. The results were evaluated by using standards stratit5ed according to age and sex. Among the dispensar-ized Children there were significantly more Children with low C3 and C4 levels and with higher IgA concentrations. The IgM and IgG concentrations did not differ.
Key words:
child population, allergic diseases, immunoglobulins, Complement, concentrations of the serum
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