Helicobacter pylori (Hp) is the most common chronic bacterial infection in humans. Hp has been
demonstrated worldwide and in individuals of all ages. The overall prevalence of Hp infection has fallen
dramatically in the Czech Republic over recent 15 years (from 70 % in 1993 to 35 % in 2006). This
decrease can be explained mostly by the relatively favourable and improving socioeconomic conditions
after the fall of communist regime. However, it is necessary to consider also the fundamental determinants
of “modern times” that could cause gradual disappearing of Hp from the human “microbiome”.
Helicobacter pylori, decrease of prevalence.