The diagnostice and the treatment of the disorders of the thyroid gland in pregnancy belong to the most important topics for most endocrinologists in the whole world. Untreated or mistreated thyroid gland disorders may influence the course of pregnancy and development of the foetus and child. Autoimmune thyroiditis, hyperthyroidism and hypothyroidism represent the most common thyreopaties in pregnancy and that is why the aim of the study was to establish their prevalence in population of pregnant women of the West Bohemia region. In our study we assessed serum levels of thyrotropin (TSH), free tyroxin (fr4) and antithyroid perogidase antibodies (antiTPO) in 650 pregnant women. Sera esere acquired during routine blond sampling for Down syndrome screening in the 2nd trimester of pregnancy. In our group we found the prevalence of 1.5 % of hypothyroidism and 9.4 % of autoimmune thyroiditis and we revealed no case of thyrotogicosis, only subnormal TSH in 2.3 %.

        Key words: Pregnancy - Thyroid gland - Hyperthyroidism - Hypothyroidism - Autoimmune thyroiditis