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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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| Česky / Czech version | Soud. Lék., 48, 2003, No. 4, p. 54 - 56 |
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The Relation of some Posttranslational Modifications of Proteins of Human
Tissues to the Age and their Application for Age Estimation in Forensic
Medicine. A Review of Knowledge Pilin A.1, Pudil F.2, Sajdok J.3, Zídková J.4, Bezdíčková D.5, Bencko V.6 1Ústav soudního lékařství a toxikologie 1. LF UK a VFN, Praha 2Ústav chemie a analýzy potravin Fakulty potravinářské a biochemické technologieVŠCHT, Praha3Ústav biochemie a mikrobiologie Fakulty potravinářské a biochemické technologie VŠCHT, Praha4Ústav biochemie a mikrobiologie Fakulty potravinářské a biochemické technologieVŠCHT, Praha 5Ústav klinické biochemie 1. LF UK a VFN, Praha6Ústav hygieny a epidemiologie 1. LF UK, Praha |
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Summary: This article deals with some of posttranslational modifications of proteins which are, or could be
useful to work out objective and standard methods for age estimation in forensic medicine. From
many posttranslational modifications other than racemization, the evaluation of pentosidine, one
of the products of nonenzymatic glycosylation, seems to be promising. The enlargement of menu
of methods for age estimation is important mainly for forensic sciences when determination of
the age of an unknown dead body is necessary. Morphological methods are quite often subjective
and charged with errors.
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