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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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| Česky / Czech version | Čs. Derm., 76, 2001, No. 3, p. 135-137 |
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Functional Granulocyte Defect with Dermal Manifestations Reminding of Acne Daňková E.1 Havranová M.1, Honzová S.1, Wankatová H.2 1Imunologické centrum, Praha 2Centrum komplexní diagnostiky a terapie, Praha |
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Summary: The authors present the case of a 39-year-old woman who was treated for 14 years at the dermatological department on account of acne. Immunological laboratory tests revealed serious impairment of granulocyte function. 74 % granulocytes were unable to react to stimulation by an oxidative response on examination on a flow cytometer. This disorder is typical for chronic granulomatous disease. After initiation of treatment with systemic antistaphylococcal antibiotics marked improvement of the dermal symptomatology was recorded.
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