In patients with stricture of urethra and lacking autologous tissue, the reconstruction of urethra requires alternative material. In such cases we have used an acellular collagen matrix prepared from submucosa of the pig intestine. The material is supplied by the Cook company as a preparation for strengthening abdominal wall in the hernia plasty and to solve stress incontinence in women. The material is easily available and adjustable for a correct size; the manipulation is simple as well as implantation in the region of urethra by the on lay technique. The use of acellular collagen matrix represents a simple method for solving strictures of urethra, which are not suitable for resection and anastomosis. The endoscopic control in the early post-operation period revealed a good epithelization of the graft. The evaluation of results requires a large cohort of patients observed for the period of at least one year.

        Key words: stricture of urethra,on lay technique, acellular collagen matrix