The case of 8 years old female with an acute bullous eruption on the trunk and limbs, forming bizarre rosette-like pattern is described. Results of clinical, histological and direct immunofluorescence examinations were suggestive for the diagnosis of pemphigus. The patient was treated with the leukotriene antagonist montelukast for chronic asthmatic bronchitis started 5 months before the onset of skin eruption. The montelukast was withdrawn and the disease gradually subsided after administration of systemic corticosteroids and dapsone. Sporadic pemphigus is very rare in small children. To our knowledge, there have been no previous case reports of pemphigus associated with montelukast administration.

        Key words: sporadic pemphigus in children - case report - montelukast