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  Česky / Czech version Čes.-slov. Pediat., 58, 2003, No. 2, p. 59-62.
 
24-hours Assessment of Blood Pressure in Children with Polycystic Kidney Disease 
Lehotská V.1, Kernová T.2, Chromek M.1, Kovács L.1 

II. detská klinika LFUK a DFNsP, Bratislava1 prednosta prof. MUDr. L. Kovács, DrSc. MPHKomplexné nefrologické centrum NEDIA, s.r.o., Bratislava2 primárka MUDr. B. Kozová
 


Summary:

       The authors used 24-hour ambulatory blood pressure monitoring (ABPM) in 26 children 7 - 18 years old with autosomal dominant polycystic kidney disease (ADPKD). The investigation was performed with the oscillometric device SpaceLabs 90207 during the day between 8 a.m. and 8 p.m. time in 20 minutes intervals and during the night between 12 p.m. and 6 a.m. in 30 minutes intervals. They assessed 24 hoursmean systolic and diastolic blood pressure, mean daily and mean nocturnal systolic and diastolic blood pressure. Dipping - the percentage of the decrease of systolic and diastolic blood pressure (BP) during the night was calculated. The values were compared with normal values related to the patients height according to Soergel et al. As hypertension values over 95 percentiles were considered. There was hypertension in all followed parameters in 4 children. Isolated increase of systolic blood pressure during some recorded time period was present in 3 patients, isolated increase of diastolic BP in 5 and reduced dipping totally in 10 patients, from them as isolated finding in 5 patients. Pathologic changes of BP were found in 17 (65%) children with ADPKD. Variability of some values of BP recorded only during one ABPMdid not allowto consider which of the followed factors is the most important risk factor for the development of renal progression. Long-term follow-up and repeated ABPM are necessary.

        Key words: ambulatory blood pressure monitoring, polycystic kidney disease
       

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