CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ | |
Journals - Article | |
Česky / Czech version | Čes.-slov. Pediat., 58, 2003, No. 2, p. 59-62. |
24-hours Assessment of Blood Pressure in Children with Polycystic Kidney Disease Lehotská V.1, Kernová T.2, Chromek M.1, Kovács L.1 II. detská klinika LFUK a DFNsP, Bratislava1 prednosta prof. MUDr. L. Kovács, DrSc. MPHKomplexné nefrologické centrum NEDIA, s.r.o., Bratislava2 primárka MUDr. B. Kozová |
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Summary: The authors used 24-hour ambulatory blood pressure monitoring (ABPM) in 26 children 7 - 18 years old with
autosomal dominant polycystic kidney disease (ADPKD). The investigation was performed with the oscillometric
device SpaceLabs 90207 during the day between 8 a.m. and 8 p.m. time in 20 minutes intervals and during the
night between 12 p.m. and 6 a.m. in 30 minutes intervals. They assessed 24 hoursmean systolic and diastolic blood
pressure, mean daily and mean nocturnal systolic and diastolic blood pressure. Dipping - the percentage of the
decrease of systolic and diastolic blood pressure (BP) during the night was calculated. The values were compared
with normal values related to the patients height according to Soergel et al. As hypertension values over 95
percentiles were considered.
There was hypertension in all followed parameters in 4 children. Isolated increase of systolic blood pressure
during some recorded time period was present in 3 patients, isolated increase of diastolic BP in 5 and reduced
dipping totally in 10 patients, from them as isolated finding in 5 patients. Pathologic changes of BP were found in
17 (65%) children with ADPKD.
Variability of some values of BP recorded only during one ABPMdid not allowto consider which of the followed
factors is the most important risk factor for the development of renal progression. Long-term follow-up and
repeated ABPM are necessary.
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