Acute Phase Response, Serum Interleukin-6 and Circulating Immune
Complexes in Patients with Duodenal Ulcers before and after Eradication of Helicobac-
ter pylori
Rejchrt S. 1 , Drahošová M. 2 , Tichý M. 1 , Andrýs C. 2 , Krejsek J. 2 , Konštacký M. 1 ,
Živný P. 3 , Palička V. 3 , Bureš J. 1
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Summary:
The aim of the study was to evaluate the systemic response to Helicobacter pylori (HP) infection. The acute
phase response was studied in 21 patients with duodenal ulcers before and 4 weeks after eradication therapy.
Serum interleukin-6, C-reactive protein, haptoglobin, acid a1-orosomucoid and circulating immune complexes
were assessed. We failed to find elevated values neither of serum interleukin-6, C-reactive protein, haptoglobin,
acid a1-orosomucoid nor circulating immune complexes before eradication therapy. There was no significant
difference in those values after successful HP eradication.
Key words:
Helicobacter pylori, acute phase response, interleukin-6, circulating immune complexes, eradication
therapy.
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