Functional changes of antireflux mechanisms after laparoscopic fundpolication. Aim: To examine manometry and pH-study in evaluation of the changes in measurable features of antireflux mechanisms after fundoplication for gastro-oesophageal reflux disease. Methods: Laparoscopic Nissen-Rossetti fundoplications with hiatorhaphy were performed in patients with gastroesophageal reflux disease. Preoperative and postoperative manometry and pH-study were compared in set of twenty satisfied orjerated without any complaints after surgery who agreed with preoperative and postoperative examinations. Results: Higher lenght of lower esophageal sphincter following antireflux fundoplication (P = 0.0003), increased tone of lower esophageal sphincter with antireflux fundoplication (P = 0.0001) and lower value of pH-study after fundoplication (P = 0.0001) were observed. Conclusion: Postoperative manometry and pH-study effectively evaluated gastro-oesophageal reflux changes following fundoplication for gastro-oesophageal reflux disease

        Key words: gastroesophageal reflux – manometry – pH-study – fundoplication