Introduction: Glucometer and strips systems (GSS) approved for home use should calibrate their B-glucose (BG) readings to plasma glucose values (PG) measured by laboratory analyzers. Nevertheless, differences between some meter- and lab values appear. Objective: To check accuracy (mean PG - mean BG) and precision (SD) of four GSS (one Advance, Hypoguard; two Cards, Medisense; one Optium, Medisense) and to find simple correction factors to equalize their readings to the lab results. Material and Methods: Five samples of heparinized blood were prepared by spiking method to contain 2, 5, 15, 20 and 30mMglucose,then kept at 24–28 °C and,one after another, investigated. In each sample,PGwas estimated 20 times (within 12 min) by the analyzer IL 600 (Instrument Laboratory, USA) and, at the same time, BG was estimated 20 times in each of four GSS using one batch of respective strips. Statistical program SPSS v. 10.1 was used to analyze the data, including the error-grid analysis. Results: In all tested systems, despite of different accuracy and precision, there was a strong correlation between BG and PG (r > 0.98), allowing to apply the linear regression to convert the displayed BG to PG value when necessary. So, in Advance, PG [mM] ≈  - !-" #$%  ' $ ()* ≈ !- !-" #$%  +&, $ ()* ≈ - !-! #$- Conclusion: All the tested systems are acceptable for daily routine.However, patients and health care providers should be informed about conversion of BG values monitored by their GSS to laboratory PG values. Internal quality control of glucometer systems used in health services should be regularly performed.

        Key words: selfmonitoring, P-glucose, B-glucose, accuracy, precision, diabetes mellitus.