Summary:
Bone scintigraphy using 99m Tc phosphate complexes is a suitable method for diagnosis and study of Legg-Cal-
vé-Perthes disease (LCPD). The localization of the radiopharmaceutical in bone depends on bone perfusion and
metabolism.
Legg-Calvé-Perthes disease is considered as avascular necrosis of the proximal femoral epiphysis, that can
result in a secondary arthrosis. One of the main theories of development of avascular necrosis suggests vascular
damage with production of an arterial or venous thrombosis of blood vessels of the epiphysis. Avascular necrosis
with revascularization during the disease has several scintigraphic images. Conway’s scintigraphic classification
of LCPD is derived from this theory. Conway differentiates two principal mechanisms of revascularization: 1.
recanalisation stage A with recanalization of the existing vessels, 2. neovascularization - stage B, with formation
of new vessels. These 2 principal stages are devided into substage 1 - 4. Bone scintigraphy was used to examine 67
children (51 boys, 16 girls), those suffering from hip or knee pain with a limp were suspected of LCPD. Trauma
and large strain during the sport activities were often present. 31 children suffered from LCPD. A pathological
scintigram of the hip was found in all these children. From 36 children with a negative or equivocal X-ray only in
8 children a pathological scintigram was found. A stage A - recanalization associated with good prognosis was
appeared in 25 children. A stage B - neovascularization associated with a foorer prognosis was found in 16 children.
The correlation of scintigraphy of the hip with X-ray examination is necessary for the correct diagnosis of stage
of LCPD according to Conway’s criteria. In our experience Conway’s classification is useful for evaluation of the
development of the disease; this is important for the prognosis and treatment of LCPD.
Key words:
Legg-Calvé-Perthes disease, bone scintigraphy, Conway’s scintigraphic classification
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