In 1994-1998 in the Easte Bohemian region 78 occupational cases of bronchial asthma were reported. Most frequently the disease developed durin processing of flour, in agriculture, in the textile industry and in the health services. The most important allergens were flour, plant and animal dusts in agriculture, textile dusts and disinfectants. Attention is drawn to the fact that according to a new list of occupational diseases also allergic rhinitis can be notified as an occupational disease. Early re-allocation in case of initial forms of allergic diseases of the airways can prevent the development of bronchial astma.

        Key words: bronchial asthma - occupational disease - occupational allergens.