The authors describe the case of a 42-year-old man with refractory itching of the skin persisting for years and the formation of multiple pruriginous papulonodular lesions on the trunk and extremities. In a bioptic specimen from a fully developed lesion the authors revealed in the dermis proliferation of the capillaries with enlarged endothelial cells surrounded by histiocytes, with a small number of lymphocytes and eosinophils. Mitotic activity was not found. Between capillary aggregates agglomerations of fine peripheral nerve fibres were found. The histological finding is consistent with angioendotheliomatosis.

        Key words: reactive angioendotheliomatosis - histopathological picture - case-report