The review article is focused on one of the wide range of pharmaceutically and medicinally
employed cellulose derivates – oxycellulose. This substance, prepared by oxidation of cellulose, in
contrast to cellulose esters and ethers, has not been not employed in practice in a wide extent yet.
However, recent studies reveal its potential use in modern therapeutical systems, whether as
a release-modifying excipient, a drug carrier, or also an active substance with ability of hemostasis,
prevention of tissue adhesion after surgical operations, and a substance with antimicrobial and
immunomodulating activity, whose unique property of biodegradability, promoted by
hypoallergenicity and non-irritability, has not been observed in any of the hitherto used cellulose
derivates. The article presents a comprehensive overview about the history of this derivate, from its
physico-chemical properties through the description of the ability of biodegradability to its already
realized and planned utilization.
oxycellulose – oxidized cellulose – biodegradability – hemostasia – modern