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  Česky / Czech version Čas. Lék. čes., 142, 2003, No. 8, p. 451–455.
 
Functional Gastrointestinal Disorders at the Beginning of the 21st Century – New Things in Ethiopathogenesis, Diagnostics and Therapy 
Novotný A. 

IV. interní klinika 1. LF UK a VFN, Praha
 


Summary:

       Author presents an overview of ethiopathogenic factors, diagnostic and therapeutical possibilities of functional gastrointestinal disorders. The key role in ethipathogenesis is now credited to the motility disorders, visceral hypersensitivity, psychosocial factors and to neurohumoral agents. Diagnosis is still difficult because of the polymorphic clinical signs. In praxis the disease is often diagnosed by excluding organic causes of complaints. Therapy includes awide scale of remedies. The choice depends on the clinical symptomatology. Therapeutic approach must be complex; beside the pharmacological treatment, an important place has psychotherapy and improvement of the personal regime. In spite of the present progress, it is necessary to widen our knowledge on the ethiopathogesy and thus to improve the diagnostic and therapeutic possibilities.

        Key words: functional disorders, dyspepsia, visceral hypersensitivity, Rome criteria, serotonine (5-hydroxytryptamine), prokinetic drugs.
       

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