The authors describe a fatal case of tertian malaria (Plasmodium vivax) imported to the Czech Republic from India. Severe clinical symptoms leading to shock and multi-organ failure are more frequent in tropical malaria (P. falciparum). Despite the use oc continuous veno-venous haemodiafiltration HLA-DR decline and death occurred. The effect of the administered antimalarias drugs was good.

        Key words: lethal tertian malaria (Plasmodium vivax), veno-venous haemodiafiltration, HLA-DR, quinine.